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Proteasome: Proteasome subunit

PAG Title Proteasome: Proteasome subunit
PAG ID PEX001185
Type A
Source Link Pfam
Publication Reference NA
PAG Description The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes 1. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria 1. The second is call beta-proteobacteria proteasome homologue (BPH) 1.
Species Homo sapiens
nCoCo Score 1,227
Base PAG ID PEX001185
Human Phenotyte Annotation
Curator PAGER curation team
Curator Contact PAGER-contact@googlegroups.com
Gene ID Gene symbol Gene name RP_score
Gene A Gene B Source SCORE

Gene A Gene B Mechanism Source
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