Proteasome: Proteasome subunit
| PAG Title | Proteasome: Proteasome subunit |
| PAG ID | PEX001185 |
| Type | A |
| Source Link |  Pfam |
| Publication Reference | NA |
| PAG Description | The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes 1. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria 1. The second is call beta-proteobacteria proteasome homologue (BPH) 1. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 1,227 |
| Information Content | Rich |
| Other IDs | PF00227 |
| Base PAG ID | PEX001185 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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